by The rates of colorectal and other stomach -intestine cancer are increasing in Americans under the age of 50, the researchers said on Tuesday.
You may know why. An increased risk of early gastrointestinal cancer is associated with obesity, which also increases in the United States, what scientists say that the “leading theory” for the increase was a study from 2019, in which women who were considered to be obese, the risk of developing an early colorectal cancer for the early onset cancer almost twice as high. According to studies that were published in the same year, half of all US people grow by 2030 will probably be obese by 2030.
The chronic disease can lead to inflammation and higher insulin levels, which, according to the centers for the control and prevention of diseases, increase risk of cancer, including several types of gastrointestinal cancer. Other risk factors are smoking, drinking alcohol, eating a western style diet and non -alcoholic fatty liver disease.
At the beginning of this year, new studies referred to the effects of a toxin in the intestine, which is known as a colibactin and the colon cells that lead to the development of cancer can cause DNA damage. Colibactin is produced by the bacteria E. coli, which is often responsible for food diseases.
The specific cause remains unclear from now on, but the United States is not alone, the researchers said.
“The incidence of GI cancer in adults that rise under 50 years under 50 is increasing worldwide”
Stomach -intestine cancer rates in the USA
In the United States, scientists found that early cases in the early stations have shown a “significant increase” in American men and women since the mid -nineties.
Compared to American adults born in 1950, those who were born in 1990 have twice as high as the risk of developing colon cancer, and four times the risk of developing rectal cancer, as the researchers stated.
In addition, early colon cancer has become the most common cause of cancer -related deaths in men under the age of 50. For women in the same age group, this is the second cause of cancer -related deaths.
Colon cancer, the most common type of gastrointestinal cancer, also has a disproportionate effect through the black, Hispanic, indigenous and Asian population.
Changing treatment
These and other related findings signal a worrying shift – and possibly a need for updated treatment practices, according to the researchers.
Patients with early colorectal cancer often have delays in diagnosis, since neither doctors nor their patients that cancer and doctors diagnose patients with greater probability if they are in advanced stages of the disease. Younger patients are more likely to receive aggressive treatment, “often without survival advantage,” they said.
Colon cancer is the third -party cause of cancer -related deaths in American men and the quarter -headed cause in women. Overall, it is the second most common cause of the deaths of US Cancer, and the American Cancer Society is expected to cause 52,900 deaths this year.
The researchers pointed out that younger patients have more financial difficulties based on their diagnosis and problems with body image and mental health as well as a poor quality of life.
“Constant research efforts to investigate the biology of early GI cancer are crucial for the development of more effective screening, prevention and treatment strategies,” said Char, the senior author of the newspaper.
The paper was published by Oxford University Press in the magazine BJS.
